Chemists

**Work Schedule**

Standard (Mon-Fri)

**Environmental Conditions**

Will work with hazardous/toxic materials

**Job Description**

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

**Discover Impactful Work**

This opening is for a highly qualified and self-motivated individual to support our latest generation Ion Chromatography (IC) instrumentation as a field-based Application Scientist. As a member of the Thermo Fisher Scientific North Americas application support team, the candidate will work within a multi-disciplinary matrix team that includes regional sales representatives, marketing and service professionals, product development scientists, and engineers.

**A day in the life**

+ Provide training on how to use Thermo Scientific's Ion Chromatography instruments and software for a wide range of applications, both in person and remotely.

+ Provide pre- and post-sales technical support as well as applications assistance in response to customer inquiries, including education, training and on-site visits.

+ Connect with customers in a professional manner.

+ Build well-organized information-rich tools (documents and seminars) and effectively deliver them in an engaging manner.

+ Combine conceptual and analytical knowledge to independently address difficult problems.

+ Prioritize projects to most effectively accomplish core job functions.

**Keys to Success**

**Education**

+ A bachelor’s degree in chemistry, biochemistry, or a related scientific field and/or equivalent work experience.

+ Research experience, such as a Masters or a Ph.D. or equivalent experience, is an asset.

**Experience**

+ 3+ years of hands-on IC experience.

+ High Pressure Liquid Chromatography (HPLC) experience a plus

**Knowledge, Skills and Abilities**

+ This position involves frequent interaction with customers, so excellent verbal and written communication skills are a must.

+ A consistent track record of working independently and a strong work ethic are essential.

+ Ability to travel up to 75% mainly within Northeastern United States with occasional international travel, primarily to the Canada.

**Benefits**

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

**Compensation and Benefits**

The salary range estimated for this position based in New Jersey is $83,300.00–$125,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

+ A choice of national medical and dental plans, and a national vision plan, including health incentive programs

+ Employee assistance and family support programs, including commuter benefits and tuition reimbursement

+ At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

+ Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

+ Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

For immediate consideration, please connect with me on LinkedIn at https://www.linkedin.com/in/dpotapenko and then email your resume, work authorization status, current location, availability, and compensation expectations directly to [email protected] - make sure to include the exact job title and job location in your email message.

*** The job is on-site with a HYBRID work schedule. Candidates must be local or willing to relocate within commuting distance of Chicago IL, Pittsburgh PA, Wilmington DE

Lead Data Scientist :

- Lead various analytical projects for credit card decision science initiatives

- Supervise junior analysts

- Create data-driven presentations for product team collaboration

- Develop and implement consumer lending strategies

- Design and execute machine learning models for credit decisioning

- Analyze large-scale credit card portfolio performance

Required Qualifications (Skills, Experience, Education, Certifications) :

- Master's degree in Statistics, Mathematics, Computer Science, or related quantitative field

- Experience in consumer lending data analytics, preferably with a major financial institution ( ideally a mid-to-large bank or a fintech lender – building strategies for originating new loans/credit cards; and/or building strategies for managing an existing portfolio of loans/credit cards )

- Experience with credit bureau attributes and internal risk/return metrics of a consumer lending product (preferably credit card)

- Experience in querying, analyzing and synthesizing large consumer lending datasets that provide credit profiles of various account originations along with their performance from a delinquency, loss, and revenue standpoint.

- Should bring to the table expertise in consumer lending (preferably credit care) performance data analysis along with a foundational knowledge of Machine Learning techniques

- Experience with Python / PySpark for large-scale data analysis

- Experience with data visualization tools, particularly Tableau

- Experience with statistical analysis and machine learning model development

- Experience working in a fast-paced environment partnering with various stakeholders (e.g. Product and Credit Risk teams) to simultaneously manage multiple ongoing changes in lending strategies.

- Experience reviewing the work of junior analysts and providing feedback.

For immediate consideration, please connect with me on LinkedIn at https://www.linkedin.com/in/dpotapenko and then email your resume, work authorization status, current location, availability, and compensation expectations directly to [email protected] - make sure to include the exact job title and job location in your email message.

.

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

For immediate consideration, please connect with me on LinkedIn at https://www.linkedin.com/in/dpotapenko and then email your resume, work authorization status, current location, availability, and compensation expectations directly to [email protected] - make sure to include the exact job title and job location in your email message.

*** The job is on-site with a HYBRID work schedule. Candidates must be local or willing to relocate within commuting distance of Chicago IL, Pittsburgh PA, Wilmington DE

Lead Data Scientist :

- Lead various analytical projects for credit card decision science initiatives

- Supervise junior analysts

- Create data-driven presentations for product team collaboration

- Develop and implement consumer lending strategies

- Design and execute machine learning models for credit decisioning

- Analyze large-scale credit card portfolio performance

Required Qualifications (Skills, Experience, Education, Certifications) :

- Master's degree in Statistics, Mathematics, Computer Science, or related quantitative field

- Experience in consumer lending data analytics, preferably with a major financial institution ( ideally a mid-to-large bank or a fintech lender – building strategies for originating new loans/credit cards; and/or building strategies for managing an existing portfolio of loans/credit cards )

- Experience with credit bureau attributes and internal risk/return metrics of a consumer lending product (preferably credit card)

- Experience in querying, analyzing and synthesizing large consumer lending datasets that provide credit profiles of various account originations along with their performance from a delinquency, loss, and revenue standpoint.

- Should bring to the table expertise in consumer lending (preferably credit care) performance data analysis along with a foundational knowledge of Machine Learning techniques

- Experience with Python / PySpark for large-scale data analysis

- Experience with data visualization tools, particularly Tableau

- Experience with statistical analysis and machine learning model development

- Experience working in a fast-paced environment partnering with various stakeholders (e.g. Product and Credit Risk teams) to simultaneously manage multiple ongoing changes in lending strategies.

- Experience reviewing the work of junior analysts and providing feedback.

For immediate consideration, please connect with me on LinkedIn at https://www.linkedin.com/in/dpotapenko and then email your resume, work authorization status, current location, availability, and compensation expectations directly to [email protected] - make sure to include the exact job title and job location in your email message.

.

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

**Why Patients Need You**

Pfizer Worldwide Medical and Safety colleagues play a key role in connecting evidenced based, medical decision support with colleagues and stakeholders to enable better health and treatment outcomes. Whether you are creating framework necessary to ensure our evidence is scientifically sound, providing unbiased, medically necessary expertise or investigating how to close gaps in data, our mission is simple. Empower healthcare decisions regarding the safe and appropriate use of medicines for patients.

**What You Will Achieve**

It is our mission to strengthen the oversight of our clinical data through stronger ownership, control, and visibility of our clinical data. You will play an important role in processing, reviewing, and receiving patient data and records. You will be organizing clinical data forms from therapeutic groups and outside investigators. You will ensure that accurate, timely, and consistent clinical data reaches the medical department and other groups. You will be relied on for data management plans including data preparation, data validation activities, etc.

As a Manager, you provide guidance to operational teams for managing projects. Your planning skills will help in preparing forecasts for resource requirements, and providing areas of improvement for products, processes or services. Through your comprehensive knowledge of principles, concepts and theories of the discipline, you will also work towards advancing new concepts and methodologies. You will be able to take a leadership role to facilitate agreements between different teams.

It is your dedication and focus that will help make Pfizer ready to achieve new milestones and help patients across the globe.

**How You Will Achieve It**

+ Provide guidance, lead/co-lead projects, manage own time to meet objectives, plan resource requirements for projects across the division.

+ Ensure work carried out by providers is in accordance with applicable Standard Operating Procedures (SOPs) and working practices.

+ Promote the use of consistent, efficient, and quality processes to meet timelines and deliverables.

+ Serve as Clinical Data Scientist and Trial Lead for one or more clinical trials assuming responsibility for all Data Monitoring and Management (DMM) activities and interact with Clinical Data Scientist at study level for deliverables.

+ Serve as a technical resource to the study teams for data visualization and reporting tools and provide technical expertise and business process support in technology systems.

+ Ensure operational excellence in collaboration with partners for application of standards, data acquisition, proactive data review and data integrity and overall data management activities.

+ Partner with Research/Business Units and any external DM service provider to deliver high quality data management for all studies as assigned.

+ Perform central monitoring activities including review system outputs, propose suggestions for signal and action management, and follow up with study team for the action resolutions.

+ Plan and execute communication plans and methods for engaging customer populations.

**Qualifications** **Must-Have**

+ Bachelor's Degree

+ 5+ years' experience

+ Experience within the pharmaceutical industry or in a health information management role

+ Working knowledge of all phases of clinical trials and ability to assess and determine study requirement from protocol review

+ Working knowledge of clinical research, Food and Drug Administration & International Conference on Harmonization Good Clinical Practices (GCDMP), and related regulatory requirements

+ Strong Project and Risk Management

+ Strong verbal and written communication skills, demonstrated ability to handle multiple tasks and projects

+ Knowledge of Windows Environment and its applications.

**Nice-to-Have**

+ Master's degree

+ Contract Research Organization {CRO} and vendor oversight experience

+ Proficient in using commercial clinical data management systems and/or EDC products

**Other Job Details:**

+ Last Date to Apply for Job: **17 JANUARY 2025**

+ Eligible for Employee Referral Bonus

+ Not Eligible for Relocation Assistance

Work Location Assignment: Hybrid

The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Medical

\#LI-PFE

Senior Data Scientist, Molecular Modeling and Drug Discovery (Specialist Senior) - SFL Scientific

SFL Scientific, a Deloitte Business practice brings together several key capabilities to architect integrated programs that transform our clients' businesses, including Business Strategy, Environmental, Social and Governance Strategy, Technology Strategy & Business Transformation, and AI & Data Strategy.

Professionals will serve as trusted advisors to our clients, working with them to make clear data-driven choices about where to play and how to win - ultimately driving growth and enterprise value.

We are hiring a Senior Data Scientist with technical and scientific expertise in AI-based drug discovery and molecular modeling to support our team in working with clients, organizing multi-project development, and enabling technical solution delivery. Join a rapidly growing team of professionals working to build a world-class data science practice with a focus on solving complex R&D problems.

Recruiting for this role ends on 12/24/2024.

Work you'll do

As a Senior Data Scientist at SFL Scientific, a Deloitte Business, you will define data strategy, drive technical development, and help us create the next generation of tools, products, and AI services. You will work closely with clients to understand their data sets, strategy, and operational requirements in order to drive exploratory analysis and design long-term solutions. You will research, design, develop, and apply new AI/ML solutions for drug discovery and development, where you will lead the progress, validation, and interpretation of deep learning and GenAI-based pipelines for therapeutic modalities ranging from small molecules to biologics and nucleic acids.

Working with a team of interdisciplinary data scientists, engineers, architects, and consultants, our work includes novel areas such as cancer detection, drug discovery, protein design, chemical optimization, optimizing population health, and clinical trials. This is a hands-on, highly collaborative Senior Data Scientist role working on modeling complex biological data and solving challenging chemical design problems to develop tools and platforms. As a core member of the team, you will be focused on the implementation and validation of new methods and algorithms and work collaboratively with data scientists, engineers, and industry subject matter experts to aid in the research and advancement of novel protein, molecular, and discovery techniques.

+ Research and implement novel machine and deep learning approaches for Drug Discovery multimodal data, including various "omics" (transcriptomics, proteomics, etc.), biologics, small molecules, imaging, etc.

+ Work as an individual contributor to prototype data pipelines and AI-based models using state-of-the-art algorithms relevant to R&D in the biological and chemical fields.

+ Work closely with external organizations to understand their drug targets, data sets, strategy, and research requirements while driving exploratory analysis and designing long-term solutions.

+ Take responsibility for relevant data identification, collection, QC, modeling, and validation to influence and impact pre-clinical and clinical programs for our clients.

+ Guide clients with high autonomy in AI strategy and development, including understanding organizational needs, performing exploratory data analysis, building and validating models, and deploying models into production.

+ Lead client initiatives to deliver AI/ML solutions, including providing thought leadership, long-term maintenance, and AI strategy objectives.

+ Research and implement novel machine learning approaches, including advancing state-of-the-art training, solution design, network design, and hardware optimization

+ Validate AI models and algorithms via code reviews, unit, and integration tests.

+ Support prioritization of project performance and model development and ensure AI solutions are delivered to maximize business impact and new initiatives

+ Collaborate with data engineers, data scientists, project managers, and business.

+ Contribute to original research in the area of generative multimodal modeling, large language models (LLMs), diffusion models, probabilistic reasoning, and causality/causal representation learning applied to fundamental problems in life sciences.

+ Build, train, and evaluate multimodal foundation models utilizing various modern GPUs and distributed training infrastructure.

+ Work with a diverse range of multimodal and biological data types, including multi-omics data, cell/tissue images, human specimen/cohort data, bioassays, scientific literature, and more.

The Team

SFL Scientific, a Deloitte Business, is a data science professional services practice focused on strategy, technology, and solving business challenges with Artificial Intelligence (AI). The team has a proven track record serving large, market-leading organizations in the private and public sectors, successfully delivering high-quality, novel, and complex projects, and offering deep domain and scientific capabilities. Made up of experienced AI strategists, data scientists, and AI engineers, they serve as trusted advisors to executives, helping them understand and evaluate new and essential areas for AI investment and identify unique opportunities to transform their businesses.

Basic Qualifications:

+ Master's or Ph.D. in a relevant STEM field (Data Science, Computer Science, Engineering, Physics, Mathematics, Biophysics, etc.)

+ 3+ years of experience in AI/ML algorithm development and data analysis (NLP, time-series analysis, computer vision, LLMs, diffusion models)

+ 3+ years of experience in traditional ML and deep learning techniques (CNNs, RNNs, LSTMs, GANs), model tuning, and validation of developed algorithms

+ 3+ years of experience in core programming languages and data science packages (Python, Keras, Tensorflow, PyTorch, Pandas, Scikit-learn, Jupyter, etc.)

+ 3+ years of experience with deployment and optimization - Kubernetes, Docker, NVIDIA TensorRT/Triton, RAPIDs, Kubeflow, MLflow, etc.

+ 3+ years of experience with cloud deployment (AWS, Azure, GCP) preferred, such as building and scaling in AWS SageMaker or Azure ML Studio.

+ Limited immigration sponsorship may be available

+ Live within commuting distance of one of Deloitte's consulting offices

+ Ability to travel 10%, on average, based on the work you do and the clients and industries/sectors you serve

Preferred Qualifications:

+ Strong research interest in drug optimization and discovery, chemical properties prediction, computational chemistry, handling of "omics" pipelines, and cell imaging

+ 3+ years of experience in R&D, AI modeling, scientific publications, and/or solution development within drug discovery or a related discipline

+ Ability to interact at all levels of the client organization

+ Excellent verbal and written communication skills and experience in a client-facing role is preferred

Information for applicants with a need for accommodation: https://www2.deloitte.com/us/en/pages/careers/articles/join-deloitte-assistance-for-disabled-applicants.html

The wage range for this role takes into account the wide range of factors that are considered in making compensation decisions including but not limited to skill sets; experience and training; licensure and certifications; and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Deloitte, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current range is $131,175 to $218,625.

You may also be eligible to participate in a discretionary annual incentive program, subject to the rules governing the program, whereby an award, if any, depends on various factors, including, without limitation, individual and organizational performance. #MonitorDeloitte

#DeloitteJobs

#StrategyConsulting

#DeloitteStrategy

#Strategy25

#SFL25

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status, or any other legally protected basis, in accordance with applicable law.

Senior Data Scientist, Molecular Modeling and Drug Discovery (Specialist Senior) - SFL Scientific

SFL Scientific, a Deloitte Business practice brings together several key capabilities to architect integrated programs that transform our clients' businesses, including Business Strategy, Environmental, Social and Governance Strategy, Technology Strategy & Business Transformation, and AI & Data Strategy.

Professionals will serve as trusted advisors to our clients, working with them to make clear data-driven choices about where to play and how to win - ultimately driving growth and enterprise value.

We are hiring a Senior Data Scientist with technical and scientific expertise in AI-based drug discovery and molecular modeling to support our team in working with clients, organizing multi-project development, and enabling technical solution delivery. Join a rapidly growing team of professionals working to build a world-class data science practice with a focus on solving complex R&D problems.

Recruiting for this role ends on 12/24/2024.

Work you'll do

As a Senior Data Scientist at SFL Scientific, a Deloitte Business, you will define data strategy, drive technical development, and help us create the next generation of tools, products, and AI services. You will work closely with clients to understand their data sets, strategy, and operational requirements in order to drive exploratory analysis and design long-term solutions. You will research, design, develop, and apply new AI/ML solutions for drug discovery and development, where you will lead the progress, validation, and interpretation of deep learning and GenAI-based pipelines for therapeutic modalities ranging from small molecules to biologics and nucleic acids.

Working with a team of interdisciplinary data scientists, engineers, architects, and consultants, our work includes novel areas such as cancer detection, drug discovery, protein design, chemical optimization, optimizing population health, and clinical trials. This is a hands-on, highly collaborative Senior Data Scientist role working on modeling complex biological data and solving challenging chemical design problems to develop tools and platforms. As a core member of the team, you will be focused on the implementation and validation of new methods and algorithms and work collaboratively with data scientists, engineers, and industry subject matter experts to aid in the research and advancement of novel protein, molecular, and discovery techniques.

+ Research and implement novel machine and deep learning approaches for Drug Discovery multimodal data, including various "omics" (transcriptomics, proteomics, etc.), biologics, small molecules, imaging, etc.

+ Work as an individual contributor to prototype data pipelines and AI-based models using state-of-the-art algorithms relevant to R&D in the biological and chemical fields.

+ Work closely with external organizations to understand their drug targets, data sets, strategy, and research requirements while driving exploratory analysis and designing long-term solutions.

+ Take responsibility for relevant data identification, collection, QC, modeling, and validation to influence and impact pre-clinical and clinical programs for our clients.

+ Guide clients with high autonomy in AI strategy and development, including understanding organizational needs, performing exploratory data analysis, building and validating models, and deploying models into production.

+ Lead client initiatives to deliver AI/ML solutions, including providing thought leadership, long-term maintenance, and AI strategy objectives.

+ Research and implement novel machine learning approaches, including advancing state-of-the-art training, solution design, network design, and hardware optimization

+ Validate AI models and algorithms via code reviews, unit, and integration tests.

+ Support prioritization of project performance and model development and ensure AI solutions are delivered to maximize business impact and new initiatives

+ Collaborate with data engineers, data scientists, project managers, and business.

+ Contribute to original research in the area of generative multimodal modeling, large language models (LLMs), diffusion models, probabilistic reasoning, and causality/causal representation learning applied to fundamental problems in life sciences.

+ Build, train, and evaluate multimodal foundation models utilizing various modern GPUs and distributed training infrastructure.

+ Work with a diverse range of multimodal and biological data types, including multi-omics data, cell/tissue images, human specimen/cohort data, bioassays, scientific literature, and more.

The Team

SFL Scientific, a Deloitte Business, is a data science professional services practice focused on strategy, technology, and solving business challenges with Artificial Intelligence (AI). The team has a proven track record serving large, market-leading organizations in the private and public sectors, successfully delivering high-quality, novel, and complex projects, and offering deep domain and scientific capabilities. Made up of experienced AI strategists, data scientists, and AI engineers, they serve as trusted advisors to executives, helping them understand and evaluate new and essential areas for AI investment and identify unique opportunities to transform their businesses.

Basic Qualifications:

+ Master's or Ph.D. in a relevant STEM field (Data Science, Computer Science, Engineering, Physics, Mathematics, Biophysics, etc.)

+ 3+ years of experience in AI/ML algorithm development and data analysis (NLP, time-series analysis, computer vision, LLMs, diffusion models)

+ 3+ years of experience in traditional ML and deep learning techniques (CNNs, RNNs, LSTMs, GANs), model tuning, and validation of developed algorithms

+ 3+ years of experience in core programming languages and data science packages (Python, Keras, Tensorflow, PyTorch, Pandas, Scikit-learn, Jupyter, etc.)

+ 3+ years of experience with deployment and optimization - Kubernetes, Docker, NVIDIA TensorRT/Triton, RAPIDs, Kubeflow, MLflow, etc.

+ 3+ years of experience with cloud deployment (AWS, Azure, GCP) preferred, such as building and scaling in AWS SageMaker or Azure ML Studio.

+ Limited immigration sponsorship may be available

+ Live within commuting distance of one of Deloitte's consulting offices

+ Ability to travel 10%, on average, based on the work you do and the clients and industries/sectors you serve

Preferred Qualifications:

+ Strong research interest in drug optimization and discovery, chemical properties prediction, computational chemistry, handling of "omics" pipelines, and cell imaging

+ 3+ years of experience in R&D, AI modeling, scientific publications, and/or solution development within drug discovery or a related discipline

+ Ability to interact at all levels of the client organization

+ Excellent verbal and written communication skills and experience in a client-facing role is preferred

Information for applicants with a need for accommodation: https://www2.deloitte.com/us/en/pages/careers/articles/join-deloitte-assistance-for-disabled-applicants.html

The wage range for this role takes into account the wide range of factors that are considered in making compensation decisions including but not limited to skill sets; experience and training; licensure and certifications; and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Deloitte, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current range is $131,175 to $218,625.

You may also be eligible to participate in a discretionary annual incentive program, subject to the rules governing the program, whereby an award, if any, depends on various factors, including, without limitation, individual and organizational performance. #MonitorDeloitte

#DeloitteJobs

#StrategyConsulting

#DeloitteStrategy

#Strategy25

#SFL25

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status, or any other legally protected basis, in accordance with applicable law.

**Job Description**

The Center for Materials Science and Engineering (CMSE) is a comprehensive physical / materials science laboratory in the our Manufacturing Division that supports in-line supply of human-health products and important elements of new product commercialization.

We are seeking an Associate Principal Scientist/Engineer who would be excited to be responsible for experimental elucidation of root causes of atypical, defective or failed product-process materials with high business impact. Inquires typically are focused on commercial drug product, device and/or packaging, but can also include process equipment elements or incoming raw materials or components. The ideal candidate will already possess significant hands-on scientific experience in microstructural solid characterization & reporting as well as strong physical/engineering critical reasoning that promotes hypothetical thinking with respect to potential chain of causality in manufacturing or field. For this role, a learning mindset is critical—for bringing customized characterization to every investigation, understanding our manufacturing technology space , and collaborating effectively within diverse cross-functional teams that conduct and manage investigations. Strategic technical thinking is encouraged for identifying trends/patterns, contributing to risk assessments, helping teams devise strong corrective or preventative measures, and inventing new methodologies to improve our analyses. In addition to this focused role, the scientist will have the opportunity to develop and contribute within other CMSE project areas and technology initiatives.

**Required qualifications:**

+ Education Minimum Requirement: M.S. or Ph.D. in either material science, mechanical engineering, or equivalent discipline.

+ Experience Minimum Requirement: For M.S. - at least eight (8) years of industrial or relevant post doc experience; For PhD - at least four (4) years of industrial or relevant post doc experience.

+ Experimental scientist with competency and experience in one or more relevant areas: imaging/tomography, mechanical interrogation of solids or complex fluids, solid-state molecular/elemental composition.

+ Independent and technically curious thinker who loves problem solving and strives to deliver impactful analyses, devised and delivered through strong listening, flexibility, and positive collaboration that delights our partner groups on cross-functional teams.

+ Clear and effective written and verbal communication.

**Preferred experience areas:**

+ fractography & fracture mechanics

+ mechanical testing & solid mechanics

+ glass technology, polymer processing, packaging technologies

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)

Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

**US and Puerto Rico Residents Only:**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088\_EEOC\_KnowYourRights\_10\_20.pdf)

EEOC GINA Supplement​

Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp\_%20English\_formattedESQA508c.pdf)

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status:**

Regular

**Relocation:**

Domestic

**VISA Sponsorship:**

No

**Travel Requirements:**

10%

**Flexible Work Arrangements:**

Not Applicable

**Shift:**

1st - Day

**Valid Driving License:**

No

**Hazardous Material(s):**

n/a

**Job Posting End Date:**

12/28/2024

***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.**

**Requisition ID:** R328224

**Job Description**

_Our company’s Device Product & Process Development (DPPD) Team designs, develops, and commercializes novel biologic/drug/vaccine - device enabled combination products to achieve safe and effective delivery to their intended site of action. The DPPD Team manages the development of the device constituent of our company’s pipeline of combination products across a variety of therapy areas and routes of administration including inhalation, implantation, and injection._

**Job description**

This position will be responsible for applying their knowledge of product and process development in the (bio)pharmaceutical and/or medical device industries to set tactical and strategic direction on programs they lead to ensure high quality products and robust manufacturing processes. This position interacts extensively with subject-matter experts on the DPPD team and members of internal cross-functional product development teams from concept through product launch. Additionally, the position will ensure products and processes are developed in accordance with applicable regulatory, quality, company, and customer requirements.

This position will lead cross-functional development teams within and external to Device Development & Technology. The incumbent must be able to work well with all levels of employees and be able to effectively coordinate the execution of device development strategies. This individual will be expected to apply his/her knowledge of product design and development; manufacturing process development, qualification, and validation; and design control and risk management techniques to positively support and influence clinical and commercial combination product development and launches.

**Principal Responsibilities**

+ Lead and set direction for the device development strategy for multiple drug-device combination product development programs ranging from concept generation/selection, development, verification, and validation to launch readiness:

+ Lead the cross-functional Device Working Groups to ensure full integration of the device development activities with the clinical, regulatory, formulation, commercial and other key Ofunctions.

+ Lead the Device Development Engineering Core teams focused on development of design requirements for the combination product and engineering execution against the established requirements.

+ Represent Device Development and the project-specific Device Working Groups on cross-functional teams, including the Development and Commercialization Team (DCT). Additionally, maintain engagement with Early Development Teams (EDT) and Product Development Teams (PDT).

+ Serve as key point-of-contact with potential external device designers, developers, and suppliers for selected device technology platforms.

+ Oversee and serve as a technical integrator of all device development activities including engineering design, engineering analysis and testing, medical device design controls, risk management, test method/fixture development, design verification and validation, injection molding, automated assembly, and human factors analysis.

+ Proactively anticipate and resolve project obstacles and effectively communicate complex product technical challenges, device development strategy, timelines, milestones, and risks within our Company and with external suppliers

+ Author and review relevant portions of the regulatory submissions (INDs, IMPDs, NDAs, BLAs, etc.) for combination product programs under your leadership.

+ Lead/support/oversee clinical supplies production with respect to device component manufacture and final assembly of biologic/drug product with device constituent part.

+ Lead/support the development, implementation and continuous improvement of Device Development and Device Project Leader processes, procedures, and tools.

+ Maintain a high level of engagement in the program-specific design controls process and design history file development.

+ Stay current with new device technologies, relevant worldwide regulations, standards, and effectively share this knowledge with others.

+ Enhance our Company’s professional image and competitive advantage through publications, presentations, patents, and professional activities.

**Qualifications**

REQUIREMENTS:

+ B.A./B.S in Mechanical Engineering, Biomedical Engineering, Industrial and System Engineering, or other types of engineering plus a minimum of 10 years of combined experience in medical device and combination product development. Advanced degree is preferred.

+ 5+ years of leadership experience with deep working knowledge of device, biologic/drug product, and process development including regulatory submission and approval processes. Including development drug-device combination product or a medical device component of a combination product.

+ 5+ years of leadership experience of managing complex device or combination product development programs and leading cross-disciplinary project teams.

+ Has broad knowledge of medical device development, design controls and risk management, alongside deep knowledge in device design, requirement management, design verification, automation/process development, design validation, and control strategy.

+ Knowledge of U.S. and global medical device and healthcare regulations, including FDA combination products cGMP, Quality System Regulation, FDA Human Factors guidance, ISO 14971, 11608 and 11040, EN 62366, Council Directive 93/42/EEC, etc.

+ Proven track record of applying analytical skills in product design, development, and validation

+ Self-motivated with ability to work independently

+ Proven ability to lead team members of diverse skill sets and backgrounds

+ Strong interpersonal skills and a strategic thinker; able to influence without formal authority; ability to influence and present ideas to senior leadership

+ Excellent communication, presentation, negotiation, project management, and organizational skills

+ Experience with leading complex development projects at an enterprise level

+ Willing to travel

+ Able to multi-task continuously

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)

Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

**US and Puerto Rico Residents Only:**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088\_EEOC\_KnowYourRights\_10\_20.pdf)

EEOC GINA Supplement​

Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp\_%20English\_formattedESQA508c.pdf)

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected US salary range:

$149,400.00 - $235,100.00

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here (https://www.benefitsatmerck.com/) .

**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status:**

Regular

**Relocation:**

**VISA Sponsorship:**

**Travel Requirements:**

**Flexible Work Arrangements:**

Hybrid

**Shift:**

**Valid Driving License:**

**Hazardous Material(s):**

**Job Posting End Date:**

01/17/2025

***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.**

**Requisition ID:** R328390

**Job Description**

Our Company's Oncology organization is dedicated to delivering breakthrough innovations that extend and improve the lives of cancer patients worldwide. Our team of dauntless, forward-thinking individuals achieves this through an unwavering commitment to supporting accessibility to medicine, providing new therapeutic procedures, and collaborating with governments and payers to ensure that people who need medicines have access to them. At our Company, our focus is on innovation and launch execution excellence; we translate breakthrough science into innovative medicines that help people with cancer across the globe.

Working with ADT’s, early- & late-stage clinical development teams, the BMx leads will develop asset-specific clinical biomarker strategy by incorporating critical insight from discovery biology, clinical development, diagnostics, bioinformatics, molecular assay experts, QP2 and BARDS.

**KEY RESPONSIBILITIES:**

+ Identify asset-specific translational deliverables & gaps. Building testable hypothesis & forming BMx strategy: collaborate across different LFs, to formulate testable clinical and translational hypotheses; and develop clinical biomarker and translational research strategy to test the hypothesis.

+ Alignment, risk mitigation & strategy implementation: align with asset development team strategy. Build critical scientific insight to identify gaps and risks, pro-actively develop mitigation plans. Work with matrixed stakeholders to ensure implementation.

+ Collaborate with Asset Development Teams, Early Development Teams; Product Development Teams, Clinical Trial Teams, Discovery, Informatics; Diagnostics, quantitative modeling team; Biostats, Molecular Assay teams, and other key LFs to author protocol-specific biomarker plans and ensure their efficient implementation.

+ Incorporate cutting edge scientific and technical advances to support clinical developments. Proactively identify and engage external KOL’s on specific hypothesis-driven collaborations to complement internal effort. Drive the publication of biomarker and translational research for respective studies.

+ Analysis, interpretation & impact: collaborate with forementioned line functions to build formal analysis plans, participate in data analysis and interpretation. Effectively communicate the study plan, update and output across different function areas to for optimal impact on projects.

+ Contribute to Health Authority engagements; Registrational Effort and Post Marketing Commitments.

+ The individual is in translational research and biomarker development for our Company's Oncology programs.

+ Working with early- and/or late-stage clinical development teams, they will have the opportunity to drive translational research and clinical biomarker development for critical oncology clinical programs.

+ The individual will assume a role in a dynamic, cross-functional environment as a key member in early- and/or late-stage development teams and work closely with multiple functional line functions in various scientific and operational aspects of translational research and biomarker development.

**Key responsibilities include, but are not limited to the following:**

+ Hypothesis-building & strategy forming collaborate with stakeholders in clinical development team(s), to formulate testable clinical hypothesis and develop clinical biomarker and translational research strategy to test the hypothesis.

+ Alignment, risk mitigation & strategy implementation: align the development team strategy with broader portfolio strategy. Build critical scientific insight to identify gaps and risks, pro-actively develop mitigation plans. Work with matrixed stakeholders to ensure implementation.

+ Analysis, interpretation & impact: collaborate with line function experts to build formal analysis plans, participate in data analysis and interpretation. Effectively communicate the study plan, update and output across different function areas to for optimal impact on projects.

**Specific responsibilities include, but are not limited to the following:**

+ Work closely with Product Development Team and/or Early Development Team stakeholders. Set protocol-level, hypothesis-driven translational science and biomarker strategy.

+ Collaborate with clinical and companion diagnostic leads, author protocol-specific biomarker plans and ensure their efficient implementation. Co-lead a regularly scheduled biomarker meeting for the development team (s).

+ Collaborate with experimental experts, bio-informatics experts, statisticians and clinical stakeholders to build formal statistical analysis plans, analysis reports and data communication plans. Participate in data analysis and interpretation.

+ Interface with translational and discovery laboratories to drive implementation of preclinical/translational projects based on emerging clinical/translational datasets.

+ Incorporate cutting edge scientific and technical advances to support clinical developments. Proactively identify and engage external KOL’s on specific hypothesis-driven collaborations to complement internal effort.

+ Drive the publication of biomarker and translational research for respective studies.

**Qualifications** **:**

+ PH.D. M.D or M.D./Ph.D. with a minimum of 10 years' experience in oncology biomarker studies and translational clinical research

**Required** **:**

+ Must have experience in clinical trial development and execution; clear strategic view on the Translational needs in clinical studies; Experience & familiarity with experimental and bioinformatic aspects of translational research and biomarker development.

+ Strong interpersonal skills, as well as the ability to function in a team environment are essential

+ A proven track record in biomedical research is essential;

+ Demonstrated record of scientific scholarship and achievement.

+ Ability to demonstrate a broad understanding of the end-to-end drug and diagnostic development process, and specific expertise in oncology, preferably immuno-oncology

+ Possess communication and analytical skills to regularly interface with a wide variety of stakeholders within the organization, as well as with external clinicians and scientists

+ Proven track record in cross-functional, highly matrixed collaborative groups on drug discovery and/or clinical development.

**Preferred** **:**

+ Prior experience in drug discovery in oncology

+ Prior experience in communication with health authorities

+ Specific expertise in immunology and/or immuno-oncology

+ Experience in companion diagnostics development

+ Project experience in biomarker discovery, biomarker and diagnostic development, and early or late drug development is desired.

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)

Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

**US and Puerto Rico Residents Only:**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088\_EEOC\_KnowYourRights\_10\_20.pdf)

EEOC GINA Supplement​

Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp\_%20English\_formattedESQA508c.pdf)

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected US salary range:

$181,600.00 - $285,800.00

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here (https://www.benefitsatmerck.com/) .

**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status:**

Regular

**Relocation:**

Domestic

**VISA Sponsorship:**

No

**Travel Requirements:**

10%

**Flexible Work Arrangements:**

Hybrid

**Shift:**

1st - Day

**Valid Driving License:**

No

**Hazardous Material(s):**

n/a

**Job Posting End Date:**

01/13/2025

***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.**

**Requisition ID:** R326755

**Job Description**

As part of Our Company’s Manufacturing Division, within the Large Molecule Science and Technology (LMS&T) organization, the Bioprocess Separation Sciences (BSS) department provides the technical process leadership and laboratory capabilities in support of late-stage pipeline and commercial manufacturing purification processes for biologics (therapeutic proteins) and vaccines. BSS supports a various combination of commercialization activities for pipeline and commercial program support, including process development and characterization laboratory experiment design and execution, technology transfer to internal and external manufacturing sites, process validation, manufacturing investigations and trend analysis, process enhancements, next generation process development, and authoring of regulatory submissions.

Under the general scientific and administrative department direction and working in conjunction with internal and external program partners, this individual will support late stage and commercial program purification activities within BSS.

**Scope includes:**

+ Responsible for laboratory-scale and/or manufacturing scale studies to support commercial process validation, characterization, and investigation evaluations, including studies performed either in-house or externally. Provides technical leadership for the design of experiments, data analysis and interpretation, as well as mentoring of junior staff. May lead a small group of lab scientists

+ Leads hands-on execution of purification development scale experiments. Typical unit operations include chromatography, ultrafiltration/diafiltration (UFDF), virus filtration, centrifugation, homogenization, and normal flow filtration

+ Provides technical leadership in the interpretations of trends observed in commercial process monitoring and for further technical investigations and process improvement changes.

+ Authors required regulatory and technical documentation. Ensures that processes are developed and documented according to our Company standard practices.

+ Coordinate staffing, inventory, waste management, equipment upkeep, budget management, data analysis, and documentation.

**Education Minimum Requirement:**

+ Degree in Biological Sciences/Chemical Engineering/Biological Engineering/Chemistry with number of years in related field: 6 years with BS, 4 years with MS, or 0 years with PhD.

**Required Experience and Skills:**

+ Some demonstrated expertise in purification of biological and/or vaccine molecules, including chromatography and/or filtration unit operations.

+ Experience with technology transfer and/or scale-up of processes to pilot and manufacturing scales for biologics and/or vaccine manufacture.

+ Excellent oral and written communication skills. Ability to effectively articulate understanding of purification process science, to drive decision making, impact assessments, design of studies and etc, in a multi-disciplinary team environment.

**Preferred Experience and Skills:**

+ Novel technology development and/or development of novel processes and application into manufacturing.

+ Knowledge of harvest, preparative chromatography, tangential flow filtration, and/or normal flow filtration desired. Demonstrated understanding of the fundamentals and/or modeling of unit operations.

+ Technical operations experience in the manufacture of biological and/or vaccine molecules at the pilot or commercial scale.

+ Prior experience in late-stage process development, process characterization, process performance qualification and validation, site readiness, batch record reviews, authoring regulatory BLA sections and working with external contract organization for development and or manufacturing.

+ Working knowledge of statistical methods for DOE design and data analysis (JMP or Design Expert software).

+ Working knowledge of statistical process control (SPC), multivariate analysis (MVA), and/or process analytical technologies (PAT) techniques for biologics and/or vaccine processes.

+ Working understanding of analytical methods to characterize biologics and/or vaccines and cGMP US/EU regulatory requirements.

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)

Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

**US and Puerto Rico Residents Only:**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088\_EEOC\_KnowYourRights\_10\_20.pdf)

EEOC GINA Supplement​

Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp\_%20English\_formattedESQA508c.pdf)

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

**U.S. Hybrid Work Model**

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status:**

Regular

**Relocation:**

Domestic

**VISA Sponsorship:**

Yes

**Travel Requirements:**

10%

**Flexible Work Arrangements:**

Not Applicable

**Shift:**

1st - Day

**Valid Driving License:**

No

**Hazardous Material(s):**

n/a

**Job Posting End Date:**

01/10/2025

***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.**

**Requisition ID:** R328302